A case of pyrexia under evaluation with ?drug induced rash
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A 66 year old lady came to casualty with complaints of fever on and off since 1 week, generalized body swelling since 1 week, decreased urine output since yesterday,SOB continuous since 2 days
She's a homemaker and she underwent a tubectomy 30 years ago and she was diagnosed with hypertension 6 years ago n was started on antihypertensive medications which she uses regularly since 5 years.she was apparently asymptomatic 1 week ago then she developed high grade intermittent fever and went to a RMP doctor for which she was treated with 2 pints NS on day 1 and again 3 pints NS on day 3 after which patient developed generalised body swelling and rashes all over the body which was erythematous macule with no specific pattern and again yesterday night and then she developed SOB since 2 days which was continuous in nature and present at rest.she doesn't have any similar complaints in the past.she complaints of decreased micturition since yesterday.there's no significant family history.
On examination patient is conscious, coherent and cooperative.
Patient has no pallor, icterus,cyanosis, clubbing,edema,lymphadenopathy
Vitals:
Temp-98.4 F
PR-88 BPM
RR-24 cpm
BP-140/80 mm Hg
Spo2-99%
GRBS-205 mg/dl
Systemic examination:
CVS- S1S2+, no murmurs heard
RS-NVBS+, BAE+
P/A- soft,NT
CNS-NFD
Provisional diagnosis:
PYREXIA UNDER EVALUATION WITH ?DRUG INDUCED RASH
INVESTIGATONS:
Haemogram:
Hb-11 gm/dl
TLC-21,700
PLT-70,000
LFT:
Tb-3.69
Db-2.30
AST-30
ALT-38
ALP-513
TP-5.6
ALB-2.28
RFT:
Urea-67
Creatinine-3.8
Uric acid-7.3
Ca-10
Phosphate-2.0
Na+-135
K+ - 3.9
Cl- -98
Urinary electrolytes:
Spot Na-211
Pottasium- 10.5
Chloride-240
ECG:
-Raised echogenicity of b/l kidneys.correlate with RFT.
-altered echogenicity of liver.correlate with LFT
XRAY:
TREATMENT GIVEN:
1) INJ.LASIX 40 MG/IV/STAT
2)INJ.AVIL 1 AMP/IV/STAT
3)INJ.NEOMOL 1GM/IV/SOS IF TEMP >102 F
4)T.PCM 650 PO/TID
5)INJ.PIPTAZ 2.25 GM/IV/TID AFTER TEST DOSE WITH 4.5 GM/IV/STAT
6)OINT.LIQUID PARAFFIN FOR L/A BD
7)IVF NS @UO+75 ML/HR
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